Challenge 5: Engineer Better Medicines
Erwin P. Bottinger, “Foundations, Promises, and Uncertainties of Personalized Medicine,”Mount Sinai Journal of Medicine 74 (2007), pp. 15-21.
Manfred Dietel and Christine Sers, “Personalized medicine and development of targeted therapies: The upcoming challenge for diagnostic molecular pathology. A review,”Virchows Arch 448 (2006), pp. 744-755.
David L. Heymann, “Resistance to Anti-Infective Drugs and the Threat to Public Health,”Cell 124 (February 24, 2006), pp. 671-675. DOI 10.1016/j.cell.2006.02.009.
W. Kalow, “Pharmacogenetics and pharmacogenomics: Origin, status, and the hope for personalized medicine,” The Pharmacogenomics Journal 6 (2006), pp. 162-165. doi:10.1038/sj.tpj.6500361
L.J. Lesko, “Personalized Medicine: Elusive Dream or Imminent Reality?” Clinical Pharmacology & Therapeutics 81 (June 2007), pp. 807-816.
M.P. Lutolf and J.A. Hubbell, “Synthetic biomaterials as instructive extracellular microenvironments for morphogenesis in tissue engineering,” Nature Biotechnology 23 (January 2005), pp. 47-55.
Gerard D. Wright and Arlene D. Sutherland, “New strategies for combatingmultidrug-resistant bacteria,” Trends in Molecular Medicine 13 (2007), pp. 260-267. doi:10.1016/j.molmed.2007.04.004.
Mike West et al., “Embracing the complexity of genomic data for personalized medicine,”Genome Research 16 (2006), pp. 559-566.
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