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Systematic Reviews for the Health Sciences

Finishing the Review

Congratulations, you are in the last steps of your systematic review!

SYNTHESIZING DATA & WRITING THE REVIEW

Extract data

Synthesize findings (Qualitative or Quantitative)

Write & Publish Review

Recommendations

MECIR (Methodological Expectations of Cochrane Intervention Reviews) Standards for Data Exptraction include:

Standard

Statement Mandatory or Highly Desired Cochrane Handbook
C44 Collect characteristics of the included studies in sufficient detail to populate a table of 'Characteristics of included studies'. Mandatory 5.3.1
C45 Use (at least) two people working independently to extract study characteristics from reports of each study, and define in advance the process for resolving disagreements. Highly Desired 5.5.2
C46 Use (at least) two people working independently to extract outcome data from reports of each study, and define in advance the process for resolving disagreements. Mandatory 5.5.2
C49 Seek key unpublished information that is missing from reports of included studies. Highly Desired 5.2.3
C50 If a study is included with more than two intervention arms, include in the review only the
interventions that meet the eligibility criteria.
Mandatory 5.3.6
C51 Compare magnitude and direction of effects reported by studies with how they are presented in the review, taking account of legitimate differences. Mandatory 5.3.6

Information taken from: https://community.cochrane.org/sites/default/files/uploads/MECIR%20Version%20February%202022.pdf

Step 19 & 20: Extract the Data and Synthesize Findings

To reduce errors and bias have two reviewers complete the data extraction and develop a plan for resolving conflicts. Determine the data you need to collect (consider if you will be conducting a qualitative synthesis only or if you will be including a meta-analysis), ideal method to collect this data, and a tool to organize data. Finally run a pilot and adjust if necessary. Commonly gathered fields include:

  • Article citation
  • Study Details (study objectives, study type, recruitment process, etc.)
  • Participant information (demographics, disease, etc.)
  • Intervention (duration, timing, etc.)
  • Outcomes

Checklist of items to consider for data extraction (see image) - 

Also consider exploring:

  1. Cochrane Handbook chapter 5
  2. Cochrane Data Extraction Form (RCTs only)

Covidence includes the option to extract data as part of the process and offers users the choice between two options.

Step 21: Write & Publish

Writing your systematic review will include all details that would allow a reader to replicate it. Various guidelines offer steps to follow when writing the review. For example, based on PRISMA and IOM guidelines the following information needs to be included in the methods section:

  • Search terms
  • Database names and interface (e.g. Medline EBSCO) and grey literature sources
  • Date of search
  • Limits and filters used
  • Resources and tools used during the process

Additional resources include:

University of Cincinnati Libraries

PO Box 210033 Cincinnati, Ohio 45221-0033

Phone: 513-556-1424

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